Thursday, January 16, 2014

First Week Results

The results of the first battery of tests is in, and they are unfortunately quite disappointing.

Tested antibiotics included the following: balofloxacin, clinafloxacin, levofloxacin, moxifloxacin, erythromycin, clarithromycin, tylocin, and telithromycin. They were all tested at both high and low concentrations, with the following less than stellar results.
  • clinafloxacin killed colonies only at doses lethal to humans.
  • erythromycin, clarithromycin, and tylocin failed to kill any colonies even at the highest doses.
  • balofloxacin and levofloxacin seem promising, working at low doses, killing about half the colonies in the agar.
  • telithromycin seems to work only at high doses.
All in all, we have four drugs that don't work feasibly for medical applications, one that the bacteria resist but can be killed by, and two that may show promise. I'll be doing further research into the Fluoroquinolones later, to see if similar drugs will work.

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